Al-ameen Abubakar Mohammed

Passionate Teaching Assistant offering 4-years background working with undergraduate students and postgraduate levels. Skilled in assisting lecturers with teaching functions, experimental planning and individual and group instruction. Talented in using various strategies to model positive behavior and maintain good laboratory practices.

• Laboratory procedures: Sound experience in conducting synthetic organic chemistry experiments; Recently synthesised novel compounds include: (diketones), benzoyl-thioureas to be tested on cancer;
• Microwave-assisted organic synthesis (green synthesis): employed MAOS in carrying out click- reactions (e.g. 1,2,3-triazoles) with chalcones
• Synthesis of metal-complexes with medicinal properties: Compounds with cancer targeting properties (recently synthesised β-diketonates of nickel (Ni) Cobalt (Co) and manganese (Mn) complexes to test for activity on different cancer cell lines);
• NMR analysis: adequate experience with 1HNMR, 13CNMR, APT, 2D-NMR (HMBC & QC) using Bruker Topspin equipment and software.

• Medical research: adequate experiment with DNA-proliferation assay (flow cytometry);
• Medical research: adequate experiment with cell-viability assay (MTT);
• Basic skills in molecular modelling and drug design tools: (Used Chimera, Swiss-Dock, Babel and Amber force-fields) for studying protein-ligand analysis on Linux platform (CentOS).
• Protein-ligand docking and identification of binding site interactions, virtual screening (VS), 3-dimensional quantitative structure-activity relationship (3D-QSAR) and identifying hit-molecule with Maestro Schrödinger software.
• Molecular Dynamic simulation: simulated different proteins and ligands to examine stability of ligand in the protein binding site.

• 2023. 5-day Workshop in Advanced Digital Empowerment Programme for Tertiary Institutions (ADEPTI) organised by Digital Bridge Institute, Abuja-Nigeria.
• 2020. Webinar training in Molecular modelling and drug design using Maestro Schrodinger package;
• 2018. 7-day Workshop in Computer Aided Drug Design – Department of Pharmacy, University of Pisa, Italy;
• 2015. Microsoft Office Excel: Analysing data – Salford Advantage workshop series, University of Salford, UK;
• 2009. Oracle Database Management and administration: SQL #1Z0-007 and Fundamentals I # 1Z0-031;
• 2009. Computer Networking: CISCO certification preparatory workshop: CCNA #640-801.

• Mohammed, A. A., Production and biological evaluation of bio-inorganic compounds as anticancer agents, ELS 1st Year symposium, presented at The University of Salford, UK, 2017.
• Mohammed, A. A. & Emmanuel O., Development of diazirine crosslinkers for covalently linking proteins, a seminar organised to present results obtained during M.Sc. lab experiments, University of Salford, UK, 2015.
• Mohammed, A. A. Determination of some anions and heavy metals from 10 boreholes in Maiduguri, Nigeria, an undergraduate seminar organised for presentation of project results, University of Maiduguri, 2011.
• Mohammed, A. A. Free and opensource software (FOSS), presented at the three-day international conference organised by Bayero University Kano and Hutsoft Nigeria Limited, 2009.

• Mohammed, A. A. (2021). Synthesis and Evaluation of a Novel Series of β-Diketones and Related Compounds as Anticancer Agents. University of Salford, UK. Unpublished PhD Dissertation.
• Mohammed, A. A. (2015). Synthesis and Development of Diazirine crosslinkers for covalently linking proteins, University of Salford, UK. Unpublished PhD Dissertation.
• Mohammed, A. A. (2011). Determination of some anions and heavy metals in ten (10) borehole waters from Bulumkutu ward, University of Maiduguri, Nigeria. Unpublished BSc Thesis.

• Mal Ullah, A.A., Mohammed, A.A. and Al Yasiri, M.J. (2024) Synthesis, Biological Evaluation, Molecular Docking and ADMET studies of Benzoyl-thiourea Derivatives and their Anticancer Activities [Preprint].
• Mal Ullah, A.A., Mohammed, A.A. and Al Yasiri, M.J. (2023) Design, Synthesis, Biological Evaluations, and Molecular Docking of Novel N-substituted Aminopyrimidine Derivatives as Anticancer Agents [Preprint].
• Busuguma U. A., Aisha M. Ngubdo and Mohammed, A. A. (2016) 'Study on the use of crosslinked polyvinyl alcohols as an after-treatment of cotton dyed with direct dyes', International Journal of pure and applied chemistry (IJBAS), 4, pp. 69-79.
• Audu, M., azumi, U. D., Garandawa, M. M., Sabo, R. and Mohammed, A. A. (2021) 'Determination of Chemical Composition and Scavenging Effectiveness of Leaf Extracts of Terminalia Catappa In Geidam Local Government Area of Yobe State, Nigeria ', JETIR, 8(1), pp. 16.

• Isolation, characterisation and identification of active components from plant extracts;
• Synthesis of novel compounds that mimic ‘medicinal natural products’.
• 3D-QSAR of active anticancer compounds for drug discovery.

• Professor Irfan Zahur Khan, Academic/Professional Mentor, Department of Chemistry, University of Maiduguri, Nigeria. Tel: +234 806 543 1029; Email: izkhan52@yahoo.co.in
• Dr John Hadfield, Academic Mentor and Supervisor, Department of Chemistry, University of Salford, Manchester, UK. Tel: +44(0) 161 2954030; Email: j.a.hadfield@salford.ac.uk
• Dr Majeed Oladokun. Academic Mentor, School of Architecture, Building and Civil Engineering , Loughborough University, UK. Tel: +44(0)1509 22263; Email: m.o.oladokun@lboro.ac.uk

• Use of Power BI (Business Intelligence) to connect disparate data sets, transform and clean the data into a data model and create charts or graphs to provide visuals of the data.
• Use of statistical packages for analysing pharmacological data (Used GraphPad prism and Origin software for analysis);
• Able to use in-built excel functions and other Microsoft Office package(s) to develop computation programs for academic records, and accounting (designed examination recording worksheets for El-Kanemi College, Maiduguri);
• Able to type at a rate of 100 wpm in English Language and 120 wpm in Arabic Language;
• Appreciable skills in calligraphy works (in English and Arabic);
• Can develop simple computer programs in: Python, Java, C++ and C programming languages;
• Querying databases with simple SQL statement and configuration of database using oracle 9i and higher versions;
• Good skills in Windows Operating System and Linux (with Ubuntu and CentOS Distribution);
• Publication of simple Web pages for tutoring, using Hypertext Mark-up Language (HTML);
• Text-based translation from Arabic language to English language and vice-versa.